Lung transplanted after 10 months on mechanical ventilation

Exceptionally prolonged mechanical ventilation seems no hinder for lung transplantation.

A minor sensation was reported recently from Okayama, Japan, in Ann Thorac Surg (Tanaka S et al, 2017) where a 10-year-old girl successfully received a donor lung from a teenage donor with hypoxic brain damage who had been on mechanical ventilation for well over 10 months.

The donor’s lungs revealed diffuse radiologic infiltration and atelectasis but excellent function, with a PaO2/FiO2 ratio of 450. According to the report, the recipient “developed grade 2 primary graft dysfunction, but recovered quickly. She is doing well and has not experienced any other critical adverse events 12 months after lung transplantation.”.


8. Tanaka S, Successful lung transplantation using a deceased donor mechanically ventilated for ten months.  Ann Thorac Surg. 2017 Aug;104(2):e177-e179 (link to abstract)

Xvivo Insights PB-2018-01-28