XVIVO LS™* & XVIVO Disposable Lung Set™

XVIVO LS™* & XVIVO Disposable Lung Set™

Compact, user-friendly device for Ex vivo Lung Perfusion (EVLP)

The XVIVO LS™ complements XPS™ as an easy-to-use EVLP device to support lung transplant teams. *XVIVO LS™ is no longer available for sale.

Increase the donor pool with a simple platform for EVLP running the Scandinavian EVLP Method.

  • Designed to simplify the EVLP process with an intuitive interface
  • Proven clinical protocol and clinical practice
  • Based on expertise and experience from clinicians

Sophisticated real-time testing and monitoring

XVIVO LS™ enables easy testing and monitoring of lung function during perfusion. The system generates perfusion data in real time, clearly displayed on dual screens so that it can be viewed from both the sterile and the unsterile side. You can measure and control pressure and flow throughout the process to minimise the risk of organ damage. Proactive user guidance enables you to quickly troubleshoot any problems.

How XVIVO LS™ works

Intuitive on-screen instructions guide you through the evaluation process step by step.

  • Priming: XVIVO LS™ and the XVIVO Disposable Lung Set™ (DLS™) are prepared for use by filling the disposable with the perfusate constisting of STEEN Solution™ mixed with washed banked erytrocytes
  • Warming: the oxygenated STEEN Solution™ is circulated and lungs are ventilated. Ventilation is initiated manually at 32 °C
  • Evaluation: de-oxygenated STEEN Solution™ is circulated and lung function can be tested
  • Cooling: the lung is cooled to preferred temperature
  • Storage: the lung is stored and kept moist and cooled until transplantation





The XVIVO LS™ enables evaluation of marginal donor lungs according to a standardized method.
STEEN Solution™
• HCT of 10–15%
• Perfusion flow: 80-100% cardiac output
• Open left atrium

Our XVIVO Disposable Lung Set™ is specially designed to fit with XVIVO LS™. The sterile disposable kit includes a lung chamber with a reservoir, an oxygenator, a leukocyte filter, pressure sensors, and tubings.

Because it is pre-assembled, it is easy and quick to set up, saving you time and effort. The donor lung is kept in the same convenient disposable unit throughout the EVLP process until transplant.

Clinical experience from two Skandinavian centres

Copenhagen University Hospital and Sahlgrenska University Hospital launched an EVLP program to increase the availability of donor lungs for transplantations. Using the XVIVO LS™ system, marginal lungs were perfused and evaluated by the Scandinavian method. The result was a significant increase in the number of lung transplantations.

The 54 patients transplanted with lungs initially rejected for transplantation but accepted after EVLP were compared to 271 lung transplant recipients receiving standard criteria donor lungs according to normal procedures at the two lung transplantation centers. The survival rate in patients receiving lungs after EVLP, up-to five years post transplantation, was not significantly different from patients receiving lungs preserved with standard cold storage.

Nilsson. T et al. 2018. Lung transplantation after ex vivo lung perfusion in two Scandinavian centres. Eur J Cardiothorac Surg. 2018 Oct 29.

To order: REF 19601; 1 box
Content: 1 XVIVO Disposable Lung Set™ (DLS™)
Packaging: Sterile pouch.
Storage: +2- +25 C degrees. Use only unopened and undamaged packages.
Shelf life: At least three months from date of shipment.
Intended use: XVIVO Disposable Lung Set™ (DLS™) is a sterile, single-use set of components to be used with XVIVO Lung System™ (LS™) for isolated donor lungs in preparation for transplantation.
Regulatory approval: The XVIVO Disposable Lung Set™ (DLS™) is available in Europe, Canada and Australia.

For more information about XVIVO LS™ please contact us.

XVIVO LS™ has been developed in collaboration with Lund University Hospital and the Igelösa Life Science Community as part of the clinical development of EVLP. The XVIVO LS™ system makes the EVLP procedure easier to perform, saving you time and effort compared to  a manually performed perfusion.