XVIVO LS™ & XVIVO Disposable Lung Set™

XVIVO LS™ & XVIVO Disposable Lung Set™

Compact, user-friendly device for XVIVO lung perfusion (EVLP)

The XVIVO LS™ complements XPS™ as an easy-to-use EVLP device to support lung transplant teams.

Increase the donor pool with a simple platform for EVLP running the Scandinavian EVLP Method.

  • Designed to simplify the EVLP process with an intuitive interface
  • Proven clinical protocol and clinical practice
  • Based on expertise and experience from clinicians

Sophisticated real-time testing and monitoring

XVIVO LS™ enables easy testing and monitoring of lung function during perfusion. The system generates clinical information in real time, clearly displayed on dual screens so everyone can see. You can measure and control pressure and flow throughout the process to minimise the risk of organ damage. Proactive user guidance enables you to quickly troubleshoot any problems.

How XVIVO LS™ works

Intuitive on-screen instructions guide you through the evaluation process step by step.

  • Priming: XVIVO LS™ and the Disposable Lung Set™ (DLS™) are prepared for use
  • Warming: the oxygenated STEEN Solution™ is circulated and lungs are ventilated
  • Evaluation: de-oxygenated STEEN Solution™ is circulated and lung function can be tested
  • Cooling: the lung is cooled to preferred temperature
  • Storage: the lung is stored and kept moist until transplantation

 

 

THE SCANDINAVIAN EVLP METHOD

 

The XVIVO LS™ enables evaluation of marginal donor lungs according to a complete and standardized method.
STEEN Solution™
• HCT of 10–15%
• Perfusion flow: 100% cardiac output
• Open left atrium

Our Disposable Lung Set™ is specially designed to enhance the performance of XVIVO LS™. The sterile disposable kit includes a lung chamber with a reservoir, an oxygenator, a leukocyte filter, pressure sensors, and hoses.

Because it is pre-assembled, it is easy and quick to set up, saving you time and effort. The donor lung is kept in the same convenient disposable unit throughout the EVLP process.

CLINICAL EXPERIENCE FROM COPENHAGEN UNIVERSITY HOSPITAL

Copenhagen University Hospital launched an EVLP program to increase the availability of donor lungs for transplantations. Using the XVIVO LS™ system, marginal lungs were perfused and evaluated by the Scandinavian method. The result was a significant increase in the number of lung transplantations.

“..Seven pairs of lungs that would normally be deemed unsuitable because they failed to meet the usual criteria for transplantation were used for transplantation after EVLP. Thus, seven out of 33 (21%) Danish lung transplantations in the period were made possible as a result of EVLP…”

Henriksen, I. et al. 2014. First Danish experience with ex vivo lung perfusion of donor lungs before transplantation. Dan Med J 61(3):1-6

To order: REF 19601; 1 box
Content: 1 Disposable Lung Set™ (DLS™)
Packaging: Sterile pouch.
Storage: +2- +25 C degrees. Use only unopened and undamaged packages.
Shelf life: At least three months from date of shipment.
Intended use: The Disposable Lung Set™ (DLS™) is a sterile, single-use set of components to be used with XVIVO Lung System (LS™) for isolated donor lungs in preparation for transplantation.
Regulatory approval: The Disposable Lung Set™ (DLS™) is available in Europe, Canada and Australia.

For more information about XVIVO LS™ please contact us.

XVIVO LS™ has been developed in collaboration with Lund University Hospital and the Igelösa Life Science Community as part of the clinical development of EVLP. The XVIVO LS™ system makes the EVLP procedure easier to perform, saving you time and effort compared to  a manually performed perfusion.