Organ Chamber™

Organ Chamber™

Single-use, sterile disposable container

The XVIVO Organ Chamber™* is a single-use, sterile disposable container intended to be used as a temporary receptacle for isolated donor lungs in preparation for eventual transplantation into a recipient.

The chamber is made of PETg and the slot enclosures are made of TPE, which is a USP Class VI biocompatible material free from phthalate plasticizers DEHP and latex.

Storage with safety and humidity in focus

The transparent lid allows for visual inspection during the EVLP process. Designed to aseptically hold the lungs and to prevent moisture loss, the XVIVO Organ Chamber™ allows the transplant team to inspect the lung without interfering in the procedure. If needed the lid can easily be opened and the lung inspected.

Designed to support

With pre-cut openings for tubing and drainage ports, the XVIVO Organ Chamber™ works together with the XVIVO Lung Cannula Set™ to support enough traction on cannulas. The cannula positions should be checked and especially a gentle traction on the LA cannula is applied to assure good patency of pulmonary veins.


  • Designed to aseptically hold the lungs during EVLP
  • Designed to prevent moisture loss during EVLP
  • Transparent lid allowing visual inspection during EVLP
  • Pre-cut openings for secure fastening of tubing
  • Opening for ventilation tubing
  • Drainage port for recycling of perfusate
  • Base designed to facilitate recycling of perfusate

In clinical usage

The XVIVO Organ Chamber™ is opened in a sterile fashion and isolated lungs are placed onto the round base section. Some centers use a cotton lap sponge placed beneath the lung to prevent excessive sliding or displacement in the chamber once ventilation starts3.

Tubing connected to the lungs are attached through the lid slots. The loose (front) lid portion is attached to aseptically seal opening and prevent moisture loss.

Endotracheal tube is passed through opening cutout near base. Tubing for drainage or other container to drain port is attached to receive any residual fluid.

Once appropriate tubing connections have been established, the lungs are connected to the extracorporeal circulation system and evaluation of lung function according to established clinical routines can commence1,2.

After the procedure the chamber is disposed according to hospital standard routines.

To order: REF 19020; 1 box
Content: 1 XVIVO Organ Chamber™ – base and lid
Packaging: Sterile poly bag, 2 layers of sterile blue surgical wrap.
Storage: Store at room temperature. Use only unopened and undamaged packages.
Shelf life: At least three months from date of shipment.
Intended Use: The XVIVO Organ Chamber™ is a single-use container intended to be used as a temporary receptacle for isolated lungs in preparation for eventual transplantation into a recipient.
Properties: Sterility assurance level 10-6
Bacterial Endotoxins (LAL assay) EU/device <20

*In the US, the XPS™ with STEEN™ Solution is indicated for use in flushing and temporary continuous normothermic machine perfusion of initially unacceptable excised donor lungs during which time the ex vivo function of the lungs can be reassessed for transplantation.


  1. Yeung J C et al. Update of donor assessment, resuscitation, and acceptance criteria, including novel techniques – Non-Heart-Beating Donor Lung Retrieval and Ex Vivo Donor Lung Perfusion. Thorac Surg Clin 2009; 19: 261-274
  2. Cypel M et al. Normothermic ex vivo lung perfusion prevents lung injury compared to extended cold preservation for transplantation. Am J Transplant 2009; 9: 1-8
  3. Machuca et al. Advances in Lung Preservation, Surg Clin N Am 93 (2013): 1373-1394,