Articles about EVLP

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Following publications describe the basic concept of EVLP.

  • Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion. Andreasson AS et al. Eur J Cardiothorac Surg. 2017 Jan 12. pii: ezw358. doi: 10.1093/ejcts/ezw358. PMID: 28082471
  • An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK. Fisher A et al. Health Technol Assess. 2016 Nov;20(85):1-276. PMID: 27897967
  • Transplantation after ex vivo lung perfusion: A midterm follow-up. Wallinder A et al. J Heart Lung Transplant. 2016 Nov;35(11):1303-1310. doi: 10.1016/j.healun.2016.05.021. PMID: 27381674
  • International Society for Heart and Lung Transplantation Donation After Circulatory Death Registry Report. Cypel M et al. International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2015 Oct;34(10):1278-82. doi: 10.1016/j.healun.2015.08.015.PMID: 26454741
  • Ventilatory Management During Normothermic Ex Vivo Lung Perfusion: Effects on Clinical Outcomes. Terragni PP et al. Transplantation. 2016 May;100(5):1128-35. doi: 10.1097/TP.0000000000000929. PMID: 26425874
  • Clinical Outcome of Patients Transplanted with Marginal Donor Lungs via Ex Vivo Lung Perfusion Compared to Standard Lung Transplantation. Fildes JE et al. Transplantation. 2015 May;99(5):1078-83. doi: 10.1097/TP.0000000000000462.PMID: 25757211
  • Lung transplantation with donation after circulatory determination of death donors and the impact of ex vivo lung perfusion. Machuca TN et al. Am J Transplant. 2015 Apr;15(4):993-1002. doi: 10.1111/ajt.13124. PMID: 25772069
  • Functional outcomes and quality of life after normothermic ex vivo lung perfusion lung transplantation. Tikkanen JM et al. J Heart Lung Transplant. 2015 Apr;34(4):547-56. doi: 10.1016/j.healun.2014.09.044. PMID: 25476845
  • Protein expression profiling predicts graft performance in clinical ex vivo lung perfusion. Machuca TN et al. Ann Surg. 2015 Mar;261(3):591-7. doi: 10.1097/SLA.0000000000000974. PMID: 25371129
  • Ex Vivo Lung Perfusion. Cypel M et al. Operative Techniques in Thoracic and Cardiovasculary Surgery 2015;19:433-442
  • Acute kidney injury after ex vivo lung perfusion (EVLP). Hauck J et al. Transplant Proc. 2014 Dec;46(10):3598-602. doi: 10.1016/j.transproceed.2014.06.068. PMID: 25498096
  • Functional outcomes and quality of life after normothermic ex vivo lung perfusion lung transplantation. Tikkanen et al. J Heart Lung Transplant. 2014 Oct 24: S1053-2498(14)01416-8
  • Experience with the first 50 ex vivo lung perfusions in clinical transplantation. Cypel M et al. J Thorac Cardiovasc Surg. 2012;144:1200-1206 Machuca et al. Advances in Lung Preservation. Surg Clin N Am 93 (2013): 1373-1394
  • State of Art: Clinical ex vivo lung perfusion: Rationale, current status, and future directions. Sanchez PG et al. J Heart Lung Transplant 2012;31:339-48
  • Ex-vivo lung perfusion. Sanchez PG et al. Curr Opin Organ Transplant. 2012 Oct;17(5):490-5
  • Clinical ex vivo lung perfusion – pushing the limits. Aigner C et al. Am J Transplant. 2012;12:1839-1847
  • Update of donor assessment, resuscitation, and acceptance criteria, including novel techniques – Non-Heart-Beating Donor Lung Retrieval and Ex Vivo Donor Lung Perfusion. Yeung J C et al. Thorac Surg Clin 2009; 19: 261-274
  • Normothermic ex vivo lung perfusion prevents lung injury compared to extended cold preservation for transplantation. Cypel M et al. Am J Transplant 2009; 9: 1-8
  • Technique for prolonged normothermic ex vivo lung perfusion. Cypel M et al.  J Heart Lung Transplant 2008;27:1319-1325
  • Transplantation of lungs from a non-heart-beating donor. Steen S et al. Lancet. 2001 Mar 17;357:825-829
  • EVLP with XPS™

    • XPS Disposable Lung Kit™ including all components needed for one EVLP procedure • Gas mix

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  • EVLP with XVIVO LS™

    • XVIVO LS Disposable Lung Set™ including all components needed for one EVLP procedure • Gas mix • STEEN Solution™

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  • EVLP with manual method

    • Hardware/Software • STEEN Solution™ • Disposables • Tubing • Gas mix

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